~~~
筋膜疼痛,怎麼治?(缺鎂鋅硒,基本建議,喝無糖豆漿+無糖紅茶。)
Lactic acidosis is found among people with Ankylosing spondylitis
在僵直性脊柱炎患者中發現乳酸性酸中毒
和上方相比
所以肩頸、筋膜、脊柱僵硬疼痛應該都是缺鎂
~~~
Parkinson’s disease (PD)
帕金森氏病(PD)
The significance of this finding adds evidencethat there is a strong
association between frozen shoulder and PD.
這一發現的意義增加了證據,證明肩周炎(五十肩)與PD有很強的聯繫。
帕金森氏症治療總整理(缺鎂鋅銅硒維它命C維它命B6,可以喝草莓亞培安素或桂格特級完膳)
The liver removes 70% of lactate.
肝臟去除了70%的乳酸。
Mitochondria-rich tissues such as skeletal and cardiac myocytes and proximal
tubule cells remove the rest of the lactate by converting it to pyruvate.
富含線粒體的組織(例如骨骼肌和心肌細胞以及近端小管細胞)
通過將剩餘的乳酸轉化為丙酮酸來去除其餘的乳酸。
Lactate Metabolism is Associated with Mammalian Mitochondria
乳酸代謝與哺乳動物的線粒體有關
Lactate enters mitochondria and is oxidized to pyruvate
乳酸進入線粒體並被氧化成丙酮酸
Lactate oxidase was shown not to be subject to product inhibition,
and to require Mg2+ as a metal cofactor.
已顯示乳酸氧化酶需要Mg2+(鎂離子)作為金屬輔因子。
Group 1; sedentary taking magnesium supplementation only (10 mg/kg/day) (Mg + S),
Group 2; subjects magnesium supplemented + training 90-120 min 5 days a week
(Mg + Training)
Group 3; training 90-120 min 5 days a week.
第1組;久坐僅補充鎂(10 mg / kg /天)
第2組;受試者補充鎂+每週5天90-120分鐘的訓練
第3組;每週5天訓練90-120分鐘。
An important decrease was determined in the lactate levels
of the 1st and 2nd groups when compared to their first measurements (p < 0.05).
第一組和第二組的乳酸水平有顯著下降(p <0.05)。
The enzyme activities of Mg2+ stimulated ATPase, creatine phosphokinase (CPK),
myokinase (MK) and lactate dehydrogenase (LDH) were determined in pooled fast
twitch (FT) and slow twitch (ST) human skeletal muscle fibers
測定了Mg2+(鎂離子)刺激骨骼肌纖維的ATPase,肌酸磷酸激酶(CPK),肌激酶(MK)
和乳酸脫氫酶(LDH)的酶活性。
All enzymes investigated demonstrated higher activities in FT fibres.
研究的所有酶均在FT纖維中顯示出更高的活性。
Mg2+ has been documented to enhance the activity of three important
mitochondrial dehydrogenases involved in energy metabolism.
Mg2+(鎂離子)已被證明可以增強參與能量代謝的三種重要線粒體脫氫酶的活性。
Regulation of mitochondrial functions by Mg2+. Mitochondrial Mg2+ activates (------>) three dehydrogenases in the mitochondrial matrix: pyruvate dehydrogenase
(conversion of mitochondrial pyruvate to acetyl coenzyme A),
isocitrate dehydrogenase (conversion of isocitrate to 2-oxoglutarate),
and 2-oxoglutarate dehydrogenase (conversion of 2-oxoglutarate to succinyl coenzyme A).
Mg2+(鎂離子)調節線粒體功能。 線粒體Mg2+激活(------>)線粒體基質中的三種脫氫酶:
丙酮酸脫氫酶(線粒體丙酮酸轉化為乙酰輔酶A),異檸檬酸脫氫酶
(異檸檬酸轉化為2-氧代戊二酸)和2-氧戊二酸脫氫酶(-)。
2-氧戊二酸酯轉化為琥珀酰輔酶A)。
Mitochondria Import Lactic Acid, Then Metabolize it; This Forms a Carrier System
for NADH Oxidation. Mitochondria possess a monocarboxylic acid transporter (MCT1)
that allows lactic acid to enter the mitochondria.
Mitochondria also possess lactic dehydrogenase, LDH,
which converts lactic acid to pyruvate.
線粒體輸入乳酸,然後代謝; 這形成了用於NADH氧化的載體系統。
線粒體具有一元羧酸轉運蛋白(MCT1),該轉運蛋白可使乳酸進入線粒體。
線粒體還具有乳酸脫氫酶LDH,該酶將乳酸轉化為丙酮酸。
When mitochondrial enzymes are inhibited, cells accumulate lactate
當線粒體酶被抑制時,細胞會積累乳酸。
這邊有提到
Table 12.2
Lactate dehydrogenase cofactor(乳酸脫氫酶輔因子):NAD
(菸鹼醯胺腺嘌呤二核苷酸【簡稱:輔酶Ⅰ,英語:Nicotinamide adenine dinucleotide,NAD+】
NAD+是去氫酶的輔酶
和維它命B3有關
含維他命B3的食物:菇類、花生、茶、豆類
所以維他命B3也能輔助乳酸代謝
總結以上:
建議補充鎂治療和身體僵硬有關的疾病。
相關文章:
漸凍人(ALS)治療總整理Part-VI最終回(缺鎂鋅錳維它命B12,建議善存+豆漿+茶。)